Browsing by Author "Ribeiro, Paulo A."

Now showing items 1-2 of 2

    • Advances in the expression and purification of human PARP1: A user-friendly protocol 

      Conceição, Carlota J.F.; Salgueiro, Bruno A.; Ribeiro, Paulo A.; Raposo, Maria; Moe, Elin (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-05)
      The PARP1 (Poly (ADP-ribose) polymerase 1) enzyme is essential for single and double-strand break repair in humans. Alterations affecting PARP1 activity have severe consequences for human health and are associated with pathologies like cancer, and metabolic and neurodegenerative disorders. Here, we have developed a fast and easy procedure for the expression and purification of PARP1. Biologically ...

    • Liposome Formulations for the Strategic Delivery of PARP1 Inhibitors: Development and Optimization 

      Conceição, Carlota J. F.; Moe, Elin; Ribeiro, Paulo A.; Raposo, Maria (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-11)
      first_pagesettingsOrder Article Reprints Open AccessArticle Liposome Formulations for the Strategic Delivery of PARP1 Inhibitors: Development and Optimization by Carlota J. F. Conceição 1,2ORCID,Elin Moe 3,4,Paulo A. Ribeiro 2ORCID andMaria Raposo 2,*ORCID 1 CEFITEC, Department of Physics, NOVA School of Science and Technology, Universidade NOVA de Lisboa, 2829-516 Caparica, Portugal 2 Laboratory ...